SNP Genotyping and Analysis: Advancing Precision Medicine
Single Nucleotide Polymorphisms (SNPs) are the most common type of genetic variation found in humans. They represent differences in a single DNA building block, called a nucleotide, and occur throughout the genome. While many SNPs have no impact on health, certain variations can significantly influence an individual’s susceptibility to diseases, response to drugs, and other health traits. SNP Genotyping and Analysis has become a cornerstone in precision medicine, enabling healthcare providers to tailor treatments to an individual’s genetic profile.
Modern SNP genotyping uses high-throughput technologies capable of analyzing millions of SNPs simultaneously. These platforms utilize microarrays, next-generation sequencing (NGS), and polymerase chain reaction (PCR)-based assays. By comparing a patient’s genetic data to reference databases, researchers and clinicians can identify disease-associated SNPs, pharmacogenomic markers, and potential targets for therapeutic intervention. This approach allows for early detection of genetic predispositions, more accurate diagnoses, and customized treatment plans.
One of the most notable…